PHA760 Biostatistics: in Pharmaceutical Development of Drugs

[3–0, 3 cr.]

The course builds on student basic knowledge of statistical theory, testing hypothesis, and bivariate analysis. The course provides a quick overview of parametric test assumptions. The course introduces techniques for setting up analysis including complex designs, multiple factors, and contrasts. Multivariable regression model is covered including assumptions, types of SS, confounding, interaction, and GOF. This is followed by a discussion of logistic regression. Modeling and interpretations are discussed with focus on odds ratios, confidence intervals and p-values. Effect size, sample size, and power of each test are covered. Active learning is encouraged thru weekly reports. Students are introduced to reporting results in formats suitable for thesis. The course emphasizes the application and interpretation from practice and utilizes computer software, namely SPSS.